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What is Alzheimer's Disease?


Alzheimer’s disease is a progressive, degenerative disease that attacks the brain and results in impaired memory. Alzheimer’s disease (AD) is the most common form of dementia. Dementia is a loss of intellectual function (thinking, remembering and reasoning) so severe that it interferes with a person’s daily functioning. AD is the fourth leading cause of death in adults after heart disease, cancer and stroke. Men and women are affected almost equally.


The disease was first described by Dr. Alois Alzheimer in 1906. Since then, researchers have developed a deeper understanding of the changes in the brain (plaques and tangles) and behavioral changes that characterize the disease. Identified risk factors are age and family. Most people diagnosed with AD are older than 65. However, AD can occur in people in the 40’s and 50’s.


Symptoms


Symptoms of AD can include gradual memory loss, decline in the ability to perform routine tasks, disorientation, difficulty in learning, loss of language skills, impairment and planning and personality changes. Communication becomes difficult as the person with AD struggles to find words, finish thoughts or follow directions. The rate of progression varies from person to person. The time from onset of symptoms until death ranges from three to 20 years with the average being eight years. Eventually persons with AD become totally incapable for caring for themselves. (For more information on symptoms, click here.)


Diagnosis


Early and careful evaluation is important because many conditions including some that are treatable or reversible can cause dementia. Potentially reversible conditions include depression, adverse drug reactions, metabolic changes and nutritional deficiencies.


There is no single clinical test to identify AD. A comprehensive evaluation to establish diagnosis will include a complete health history, physical examination, and neurological and mental status assessments and other tests including analysis of blood and urine, electrocardiogram (EKG) and chest x-rays. Documenting symptoms over time will help physicians understand the person’s illness. The physician may order additional tests as needed including: computerized topography (CT Scan), electroencephalography (EEG), formal psychiatric assessment, and/or neuropsychological testing. You will often hear that a diagnosis is made after a physician “rules out” other problems. While this type of evaluation may provide a diagnosis of AD, confirmation of AD requires examination of brain tissue, which is usually done by an autopsy. (For more information on autopsy diagnosis, click here.)


Alzheimer’s Disease Statistics


Alzheimer’s disease is a progressive, degenerative disease of the brain. The most common form of dementia is Alzheimer’s. Approximately four million Americans have AD. In Alaska, approximately four thousand individuals are diagnosed with AD.

  • 14 million Americans will have AD by the middle of the next century if a cure is not found.
  • One in 10 persons over 65 and nearly half over 85 have AD.
  • U.S. society spends at least $110 billion a year on AD. Neither Medicare nor most private health insurance covers the long-term care most patients need.
  • More than 7 of 10 people with Alzheimer’s disease live at home. Family and friends provide almost 75% of the home care. The remainder is “paid” care costing an average of $12,500 per year.
  • Alzheimer’s disease is the third most expensive disease in the United States, after heart disease and cancer.


For further information on statistics, please contact the Benjamin B. Green-Field library at (313) 335-9602.

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Alzheimer's Disease Resource Agency of Alaska
1750 Abbott Road
Anchorage, AK 99507
(907) 561-3313
www.alzalaska.org

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