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Available Therapies



Forgetfulness during later years is normal. If memory loss becomes increasingly worse, a physician should evaluate the condition to rule out dementia as the underlying cause.


Dementia is the generic term of severe memory loss and decline in reasoning.
These symptoms may be due to having or having had multiple strokes, a vitamin B12 deficiency, an under active thyroid, brain infections, long term excessive alcohol intake or Alzheimer’s.

It is important for a physician to evaluate disease early because that is when int
erventions are most helpful. Today, some dementias can be treated. Although there is no medical treatment to cure or to stop the progression of Alzheimer’s disease, some available therapies include:

 

 

  • Use of medications to treat cognitive decline and memory loss
  • Referral to appropriate activities such as exercise and recreation
  • Appropriate treatment of underlying medical or physical conditions that may affect mood or personality

Medications


The FDA has approved four medications for the treatment of Alzheimer’s disease

  • Tacrine (also known as Cognex™)
  • Donepezil hydrochloride (also known as Aricept™)
  • Rivastigmine (also known as Exelon™)
  • Galantamine hydroromide (Reminyl™)  

These medications are recommended for the early stages of Alzheimer’s and do not stop or cure the disease, but have been shown to slow the progression of the symptoms.


Cognex is the first drug the FDA approved for the treatment of Alzheimer’s disease. With the advance of other approved drugs, Cognex is not often prescribed by physicians due to its high prevalence of side effects.


Aricept is a drug that can improve memory, reasoning and other cognitive symptoms for some individuals with mild to moderate Alzheimer’s. It works by increasing the availability of acetylcholine, a specialized nerve communication chemical that is deficient in the Alzheimer’s brain.


Exelon inhibits acetyl cholinesterase and butyrlcholinesterase, two enzymes that break down acetylcholine. This inhibition increases the amount of available acetycholine, which may improve cell-to-cell communication and relieve some symptoms of Alzheimer’s. This improvement leads to better memory and intellectual function. However, Exelon does not affect the unknown factors that damage and kill nerves


Reminyl is another medication for early to moderate stage of dementia. The medication has shown beneficial effects on patient’s daily functions and ability to think.


Other drug therapies include Vitamin E, Gingko biloba and Estrogen therapy for women. For current research on Alzheimer’s, contact the National Alzheimer's Association

 

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Alzheimer's Disease Resource Agency of Alaska
1750 Abbott Road
Anchorage, AK 99507
(907) 561-3313
www.alzalaska.org

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